New IFCC reference procedures for the determination of catalytic activity concentrations of five enzymes in serum: preliminary upper reference limits obtained in hospitalized subjects
Schumann, Klauke · 2003 · Clinica Chimica Acta 327(1-2):69-79
What this work gives Aellic
Preliminary upper reference limits at 37 C with the IFCC reference procedures (97.5th percentile, hospital patients aged 17 and over), men and women: ALT 45 and 34 U/l, AST 35 and 31, gamma-GT 55 and 38, CK 171 and 145, LDH 248 and 247 U/l. The app does not use these stricter limits; its liver enzyme defaults follow the DGKL/VDGH consensus (dgkl_vdgh2005).
Correction of 25 October 2026
The registry listed alkaline phosphatase among the five enzymes (the fifth is lactate dehydrogenase) and called this paper the basis of the sex-specific limits common in German laboratories. The blood catalog cited it for limits of 50 and 35 U/l (AST, ALT) and 60 and 40 U/l (gamma-GT), which the paper does not give; those limits now cite dgkl_vdgh2005.
The entry on the register was wrong. It was not replaced but kept, with what holds instead standing next to it.
Where this sits in the engine
This work is on the register, but nothing computes with it today, mostly because the feature it belongs to has not been built yet. It is listed so the numbers on the overview do not claim more than they carry.